Articoli scientifici pubblicati

Lista di studi recenti sulla scienza, la tecnologia e la valenza clinica dell’analisi diretta del DNA  fetale isolato da sangue materno:

  1. Sparks, A.B., Wang, E.T., Struble, C.A., Barrett, W., et al, Selective analysis of cell-free DNA in maternal blood for evaluation of fetal trisomy. Prenat Diagn (2012);32(1):3-9. doi: 10.1002/pd.2922. Epub 2012 Jan 6.
  2. Sparks, A.B., Struble, C.A., Wang, E.T., Song, K., Oliphant, A., Non-invasive Prenatal Detection and Selective Analysis of Cell-free DNA Obtained from Maternal Blood: Evaluation for Trisomy 21 and Trisomy 18, Am J Obstet Gynecol. (2012), doi: 10.1016/j.ajog.2012.01.030.
  3. Ashoor, G., Syngelaki, A., Wagner, M., Birdir, C., Nicolaides, K.H., Chromosome-selective sequencing of maternal plasma cell-free DNA for first trimester detection of trisomy 21 and trisomy 18, Am J Obstet Gynecol. (2012), doi: 10.1016/j.ajog.2012.01.029.
  4. Ashoor, G., Poon L. Syngelaki, A., Mosimann B, Nicolaides, K.H., Fetal fraction in maternal plasma cell-free DNA at 11-13 weeks' gestation: effect of maternal and fetal factors, Fetal Diagn Ther. 2012;31(4):237-43. Epub 2012 May 4.
  5. Norton, M., Brar, H., Weiss, J., Karimi, A., et al. Non-Invasive Chromosomal Evaluation (NICE) Study: Results of a Multicenter, Prospective, Cohort Study for Detection of Fetal Trisomy 21 and Trisomy 18, Am J Obstet Gynecol. (2012), doi:10.1016/j.ajog.2012.05.021.
  6. Brar H, Wang E, Struble C, et al. The fetal fraction of cell-free DNA in maternal plasma is not affected by a priori risk of fetal trisomy. J Matern Fetal Neonatal Med (2012), DOI: 10.3109/14767058.2012.722731.
  7. Nicolaides KH, Syngelaki A, Ashoor G, et al. Noninvasive prenatal testing for fetal trisomies in a routinely screened first-trimester population. Am J Obstet Gynecol. 2012;207:374.e1-6.
  8. Ashoor G, Syngelaki A, Nicolaides KH, et al. Trisomy 13 detection in the first trimester of pregnancy using a chromosome-selective cell-free DNA analysis method, ULTRASOUND Obstet Gynecol. (2012), DOI: 10.1002/uog.12299.
  9. Song K, Musci T, Caughey A. Clinical Utility and Cost of Non-Invasive Prenatal Testing with cfDNA Analysis in High Risk Women Based on a U.S. Population, J Matern Fetal Neonatal Med. (2013), DOI: 10.3109/14767058.2013.770464.
  10. Fairbrother, G., Johnson, S., Musci, T. J. and Song, K. (2013), Clinical experience of noninvasive prenatal testing with cell-free DNA for fetal trisomies 21, 18, and 13, in a general screening population. Prenat. Diagn. doi: 10.1002/pd.4092.
  11. Musci, T. J., Fairbrother, G., Batey, A., Bruursema, J., Struble, C. and Song, K. (2013), Non-invasive prenatal testing with cell-free DNA: US physician attitudes toward implementation in clinical practice. Prenat. Diagn. doi: 10.1002/pd.4091.